Clinical Pharmacology and Drug Toxicity — Flashcards

Vancomycin is known to be both _____-toxic and nephro-toxic

In addition to nephrotoxicity, cyclosporine and tacrolimus may also have _____-toxicity (especially Tacrolimus)

The higher incidence of allergic reaction due to _____ local anesthetics is because of the metabolite PABA

Hint: class

_____ is also used for the treatment of Oxalic acid and Hydrofluoric acid poisoning

Toxins that require passive immunity in exposed, unvaccinated patients may be remembered with the mnemonic 'Doctor To Be Healed Very Rapidly': D: _____T: Tetanus toxinB: Botulinum toxinH: HBVV: VaricellaR: Rabies virus

Which HAART drugs are associated with peripheral neuropathy?_____

_____ syndrome results from direct activation of mast cells leading to histamine release upon vancomycin administration

Cisplatin targets the _____ cells within the organ of corti, resulting in tinnitus and sensorineural hearing loss

Neuro/Psych _____ is an anti-epileptic associated with blood dyscrasias, such as aplastic anemia and agranulocytosis

_____ is not used much anymore due to its significant side effect profile, most notably including gangrene and vasospastic (prinzmetal) angina