Clinical Pharmacology and Drug Toxicity — Flashcards

Which antibiotics (2) can prolong the QT interval? _____

Adverse effects of epoprostenol and iloprost include _____ and jaw pain

Which NNRTIs (2) are teratogenic? _____

_____ toxicities can be remembered by the mnemonic caNNOT:NephrotoxicityNeuromuscular blockadeOtotoxicityTeratogen (deafness in neonates)

Niacin may cause _____ as an adverse effect, which can precipitate gout

In addition to typical opioid adverse effects, tramadol also may cause decreased _____ threshold and serotonin syndrome

Bleomycin can cause pulmonary fibrosis due to upregulation of _____ and IL-18 in the lungs, inducing lung inflammation

_____, previously known as non-cardiogenic pulmonary edema, is an uncommon complication associated with heroin overdose.

High-dose Cladribine use can result in _____-toxicity and neuro-toxicity

Prednisolone is given at the daily dose of _____ mg/kg (max 60 mg) for 6 weeks, followed by an alternate day dose of 1.5 mg/kg (max 40 mg) for the next 6-8 weeks for Minimal Change Disease.