Cardiovascular Drugs — Flashcards

PCSK9 Inhibitors (_____ and evolocumab) work by inactivating LDL-receptor degradation, resulting in a dramatic decrease in LDL

Dyslipidemia drugs _____ upregulate the enzyme lipoprotein lipase (LPL) by activating PPAR-α

_____ inhibitors such as sildenafil (viagra) cause decreased cGMP breakdown, thus maintaining an erection

Adverse effects associated with adenosine include _____ pain and a sense of impending doom

What four drug classes are used in the treatment of primary hypertension? 1. _____2. ACE inhibitors3. Angiotensin II receptor blockers (ARBs)4. Dihydropyridine Ca2+ channel blockers

Cardiovascular/Renal_____ is a direct renin inhibitor

_____ is a newer antiarrhythmic agent indicated in atrial fibrillation.

Calcium Channel Blockers (CCBs) _____ CCBs are relatively contraindicated in patients with heart block or heart failure due to their ability to cause cardiac depression

Class I antiarrhythmics _____ the slope of phase 0 (upstroke) of the myocardial action potential

Cardiovascular (Antihypertensives) _____ is safe to use in pregnant women experiencing hypertensive emergency