Autonomic Nervous System Drugs — Flashcards

Flashcard 111: Which drugs for POAG increase trabecular outflow?_____

Answer: Pilocarpine (M3 agonists), Epinephrine, Dipivefrine and Bimatoprost (only prostaglandin) (4)

Flashcard 112: Muscle cramps in organophosphate poisoning occur due to stimulation of _____ receptors

Answer: nicotinic

Flashcard 113: Shortest acting non-depolarizing muscle relaxant not approved by FDA is _____

Answer: gantacurium

Flashcard 114: Do **quaternary** carbamates (e.g., Neostigmine, Pyridostigmine) penetrate the CNS?

Answer: No

Extra: Quaternary amines (like Neostigmine, Pyridostigmine, and Edrophonium) are polar/charged and do not cross the blood-brain barrier. In contrast, **Physostigmine** is a tertiary amine carbamate and **does** penetrate the CNS.

Flashcard 115: Which drugs are the first line treatment for POAG?_____

Answer: Prostaglandin analogues>Topical beta-blockers

Flashcard 116: Mushroom poisoning presents with signs of _____pathetic excess.

Answer: Parasympathetic

Flashcard 117: Shortest acting depolarizing muscle relaxant is _____

Answer: Succinylcholine

Flashcard 118: Shortest acting non-depolarizing muscle relaxant approved by FDA is _____

Answer: mivacurium

Flashcard 119: _____ is an alpha-adrenergic antagonist used to correct pulmonary artery vasospasm when it causes severe right left shunting soon after birth.

Answer: Tolazoline

Flashcard 120: Name a selective topical beta-1 blocker for POAG that can be used in asthma: _____

Answer: Betaxolol