Antimicrobial Agents — Flashcards

Flashcard 361: Amphotericin B colloidal dispersion contains equimolar amounts of amphotericin B and _____.

Answer: cholesteryl sulfate

Flashcard 362: _____ is the drug of choice for coccidioidal meningitis

Answer: Fluconazole

Flashcard 363: Oral terbinafine at 250 mg/day is given for a duration of _____ weeks for fingernails infection

Answer: 6

Flashcard 364: _____ is the drug of choice for human infections with Fasciola hepatica.

Answer: Triclabendazole

Flashcard 365: Which fluoroquinolone is NOT approved for use in UTIs?_____

Answer: Moxifloxacin

Flashcard 366: According to the MOHFW 2020 guidelines, which drug is the preferred **third drug** for HIV Post-Exposure Prophylaxis (PEP)?

Answer: Dolutegravir (DTG)

Extra: The preferred 3-drug PEP regimen as per MOHFW 2020 guidelines is: **Tenofovir (TDF) + Lamivudine (3TC) + Dolutegravir (DTG)** for 28 days.

Flashcard 367: _____ is the treatment of choice for chronic hepatitis-D infection

Answer: Pegylated interferon-alpha (pegIFN-α)

Flashcard 368: All contacts of diphtheria should receive antibiotic prophylaxis _____, regardless of immunization status

Answer: (benzathine penicillin G or erythromycin)

Flashcard 369: Which triple drug combination is used for mass prophylaxis and transmission interruption of filariasis?_____

Answer: Ivermectin, DEC and Albendazole

Flashcard 370: What is the primary mode of resistance to drugs like chloroquine, mefloquine, halofantrine, lumefantrine, quinine etc.?_____

Answer: Efflux pumping