Antimicrobial Agents — Flashcards

Treatment of Rabies virus includes administration of _____ and rabies immunoglobulin (passive immunization)

CMV can gain resistance to ganciclovir via mutations in the _____ gene or its DNA polymerase

Acyclovir, famciclovir, and valacyclovir are used to treat _____ VZV and HSV infections

Hint: active or latent

_____ is an irreversible -lactamase inhibitor that is combined with piperacillin (antipseudomonal penicillin) (Zosyn).

_____ is metabolized to 5-fluorouracil (5-FU) in fungal cells

Intravenous _____ and/or quinidine is used for severe malaria infections

Rifampicin _____ once a month + dapsone 100mg daily + clofazimine 300mg once a month and 50 mg daily is used to treat leprosy in adults and children older than 14 years

Helicobacter pylori quadruple therapy is a PPI, _____, metronidazole and a tetracycline

Among aminoglycoside, _____ has the highest and tobramycin has the least nephrotoxicity.

Aminoglycosides bind the _____ ribosomal subunit, irreversibly inhibiting formation of the initiation complex