Renal Pathology — Flashcards

ARPKD is secondary to a mutation of the PKHD1 gene (encodes a protein called _____) on chromosome 6p.

Renal _____ is a benign encapsulated epithelial cell tumor arising from the intercalated cells of the collecting ducts (location)

Damage to the glomerulus in Shigella-induced HUS results in platelet aggregation, _____ the platelet count when microthombi form

_____ is characterized by a 'lumpy bumpy (granular)'' immunofluorescence pattern due to immune complex deposition

Minimal change disease is characterized by _____-mediated damage of foot processes and loss of glomerular basement anions

Patients with chronic interstitial nephritis have a _____ elevation of BUN and creatinine due to a mononuclear infiltrate of tubules causing fibrosis and atrophy

Nephrotic syndrome occurs due to _____ damage disrupting the glomerular filtration charge barrier

Patients with interstitial cystitis may under go transmural fibrosis later in the disease course, leading to _____ bladder

_____ cystitis occurs because prolonged urinary retention, or intravesicular rx or BCG

Thin basement membrane lesion is characterised by diffuse thinning of the GBM, presenting with _____ w/o hearing loss or ocular abnormalities (unlike Alport syndrome)