Neoplasia — Flashcards

Elevated hCG can be a paraneoplastic syndrome, such as in _____ or large cell carcinoma of lung

Hint: neuro

Progression of colonic adenoma to carcinoma occurs with mutations in the _____ or loss of heterozygosity in the region that encodes for SMAD 2 / 4

Oral _____ and erythroplakia are precursor lesions to squamous cell carcinoma

Categories of proto-oncogenes include:_____2) Growth factor receptors3) Signal transducers4) Nuclear regulators5) Cell cycle regulators

_____ is the malignant proliferation of cells in the ducts of the breast with no invasion of the basement membrane

Bleeding may occur as a paraneoplastic syndrome in Wilm's tumor due to acquired deficiency of _____ factor or factor VII deficiency.

The t(_____,14) translocation results in overexpression of c-myc, which promotes growth

_____ -sided colorectal carcinoma usually grows as a raised (exophytic) mass

Tumor cells can evade apoptosis / immune surveillance by downregulating expression of _____ or alternative splicing of the Fas receptor

Most common malignant tumor of _____ salivary glands is Adenoid cystic carcinoma

Hint: minor/major