Neoplasia — Flashcards

Flashcard 181: Triple negative subtype of breast cancer usually has a _____ Ki67

Answer: high

Flashcard 182: Zollinger-Ellison syndrome may predispose to development of _____ tumors

Answer: carcinoid

Flashcard 183: Which subtype of rhabdomyosarcoma is associated with the worst prognosis?

Answer: Pleomorphic

Extra: Rhabdomyosarcoma Prognosis: - **Best:** Botryoid variant (of Embryonal) - **Worst:** Pleomorphic (typically seen in adults) *Note: Alveolar RMS also has a poor prognosis, significantly worse than the embryonal subtype.*

Flashcard 184: Tumors exceeding bowel wall, with lymph node invasion are classified as _____ according to Modified Duke's classification

Answer: C2

Flashcard 185: The most specific marker for gastrointestinal stromal tumor (GIST) is _____

Answer: DOG-1

Flashcard 186: Is inverted papilloma benign or malignant?_____

Answer: Pre-malignant

Flashcard 187: What is the most sensitive marker for GIST?_____

Answer: CD117

Flashcard 188: Nickel refining workers are more likely to develop _____ variety of sinonasal carcinoma

Answer: squamous cell and anaplastic (2 histological)

Flashcard 189: Identify the type of lung carcinoma that is an undifferentiated malignant epithelial tumor lacking glandular or squamous differentiation, often characterized by large cells with prominent nucleoli.

Answer: Large cell carcinoma

Flashcard 190: The definitive diagnosis of malignancy in pheochromocytomas is based exclusively on the presence of _____

Answer: metastases