Neoplasia — Flashcards

The KIT _____ encodes for the Stem Cell Factor receptor, which when bound leads to cell growth. This is a growth factor receptor found commonly in GI stromal tumor

_____ lung carcinoma may produce the anterior pituitary hormone ACTH leading to Cushing syndrome

_____ lung carcinoma arises from neuroendocrine (Kulchitsky) cells, which are small, dark blue cells

Tumors that present with **PSaMMOMA** bodies: - **P**: _____ - **S**: Somatostatinoma - **M**: Meningioma - **M**: Malignant mesothelioma - **O**: Ovarian serous papillary cystadenocarcinoma - **M**: Milk (prolactinoma) - **A**: Adenocarcinoma (Endometrial serous)

_____ syndrome is a combination of familial adenomatous polyposis with osteomas and fibromatosis

One subtype of invasive ductal carcinoma (breast) is _____ carcinoma, which is characterized by an erythematous and swollen breast that does not resolve with antibiotics

_____ is a tumor suppressor gene whose product inhibits hypoxia-inducible factor 1α (HIF-1α)

Acoustic neuromas are _____ whereas glomus tumors are non-capsulated (capsulated/non-capsulated)

Invasive lobular carcinoma grows in a _____ pattern due to lack of E-cadherin encoded by gene CDH-1

The T of TNM staging for renal cell carcinoma represents the tumor _____ and involvement of the renal vein