Molecular Basis of Cancer — Flashcards

_____ is the most commonly mutated gene in sporadic breast carcinomas

What is the first cancer to be directly associated with genetic abnormality?_____

Categories of proto-oncogenes include:_____2) Growth factor receptors3) Signal transducers4) Nuclear regulators5) Cell cycle regulators

E-cadherin overexpression is a hallmark of _____ breast carcinoma

What is the mechanism that results in malignancy from the ABL oncogene?_____

Invasive carcinomas become metastatic when they invade the _____ or blood

The following image represents the _____ carcinoma subtype of invasive ductal carcinoma (breast): hint: the circled area is lymphatics

In HPV-_____ SCC of the oral cavity, patients generally present with large primary lesions with variable nodal disease.

What type of rhabdomyosarcoma is shown in the given image? _____ **most common subtype

TNM classification of laryngeal carcinoma: No answer _____