Hematology — Flashcards

Flashcard 101: What is the most powerful prognostic indicator of multiple myeloma at the time of diagnosis?

Answer: Beta-2 microglobulin

Flashcard 102: What are the lymphocyte-related poor prognostic factors in the International Prognostic Score (IPS) for advanced Hodgkin's Lymphoma?

Answer: 1. Absolute lymphocyte count < 600/mm³ (0.6 x 10⁹/L) 2. Lymphocytes < 8% of total white blood cell count

Extra: The International Prognostic Score (IPS), also known as the Hasenclever Index, for advanced Hodgkin's Lymphoma includes 7 factors (each worth 1 point): 1. Serum albumin < 4.0 g/dL 2. Hemoglobin < 10.5 g/dL 3. Male sex 4. Age ≥ 45 years 5. Stage IV disease 6. Leukocytosis (WBC ≥ 15,000/mm³) 7. Lymphocytopenia (ALC < 600/mm³ or < 8% of WBC)

Flashcard 103: The reticulocyte count is _____ in megaloblastic anemia.

Answer: decreased

Flashcard 104: _____ are indicated for the emergency reversal of warfarin therapy in uncontrolled hemorrhage

Answer: Prothrombin Complex Concentrates

Flashcard 105: The most common presentation of heparin-induced thrombocytopenia is _____.

Answer: venous thrombosis

Flashcard 106: Anemia in a non-pregnant woman is defined as a hemoglobin level of

Answer: < 12 g/dL

Flashcard 107: Is thrombocytopenia a contraindication to bone marrow biopsy?_____

Answer: No

Flashcard 108: The most common trigger for hemolysis in G6PD deficiency is _____

Answer: infection

Flashcard 109: Which hematological abnormalities can lead to the development of nephrogenic diabetes insipidus?_____

Answer: sickle cell anemia

Flashcard 110: _____ is the only method to abort a rapidly progressing episode of acute chest syndrome

Answer: Exchange transfusion