Endocrinology — Flashcards

In patients with normal adrenal function, the metyrapone stimulation test results are _____ ACTH and increased 11-deoxycortisol

_____ insufficiency occurs when there is insufficient CRH (uncommon) or insufficient ACTH

Pseudohypoparathyroidism type 1a, or Albright hereditary osteodystrophy, is due to a defective _____ protein in the kidney and bone, which causes end-organ resistance to PTH

Gynecomastia is associated with increased levels of _____ (e.g. cirrhosis), decreased levels of androgens (ex Klinefelter syndrome), or testicular tumors (ex. Leydig cell tumor)

In primary adrenal insufficiency, the metyrapone stimulation test results are _____ ACTH with decreased 11-deoxycortisol

Decreased muscle mass and proximal limb weakness in Cushing syndrome is due to atrophy of _____-twitch (type 2) muscle fibres

Up to 25% of cases of pheochromocytoma are associated with germline mutations, including _____, VHL, and RET (MEN2A/2B)

Symptoms of Sheehan syndrome include poor _____, loss of pubic hair, and fatigue

Kallmann syndrome presents as _____ in males and amenorrhea in females; anosmia may be present in both sexes

Hyperaldosteronism presents as _____ (blood pressure) with hypernatremia (Na+), hypokalemia (K+), and metabolic alkalosis (H+)