Signal Transduction — Flashcards

The Cell Cycle is regulated by Cyclins andCyclin-Dependent Kinases (CDKs) which when _____ allow cells to bypass restriction points (checkpoints)

In the phospholipase C mechanism of cellular signaling, _____ and diacylglycerol (DAG) activate protein kinase C, which phosphorylates specific proteins to produce physiologic actions

Vibrio cholerae produces _____ toxin, which ADP-ribosylates and activates Gs resulting in a(n) increase in cAMP in epithelial cells

Cytokines such as _____ and prolactin hormone also acts by JAK STAT pathway.

TGF- is a growth factor that mediates _____ and angiogenesis. It inhibits inflammation

The insulin receptor is a tetramer consisting of two _____ subunits and two beta subunits

Glycogen phosphorylase is regulated by positive feedback by _____ via the alpha receptor (liver and muscle)

Elevated levels of hCG (e.g. choriocarcinoma) may cause _____ (males) or hyperthyroidism due to homology between hCG and TSH, FSH, and LH

Which caspase binds to Cyt c and APAF-1 complex?_____

In termination phase of hepatocyte regeneration, hepatocytes return to quiescence with the involvement of antiproliferative factors like _____