Nucleic Acid Biochemistry — Flashcards

One co-transcriptional modification is the addition of a _____ at the 5' end

Inosine is converted to _____ via the enzyme purine nucleoside phosphorylase (purine salvage)

RNA _____ uses dsRNA complementary to an mRNA of interest to "knock down" gene expression

Which base excision repair enzymes are responsible for filling and sealing the gap from the excised bases?_____ (filling) and DNA ligase III (sealing)

Hint: specific

Guanosine is converted to _____ via the enzyme purine nucleoside phosphorylase (purine salvage)

Hypoxanthine is converted to _____ via xanthine oxidase

The enzymes that repair pyrimidine dimer mutations are _____ and DNA ligase

Conversion of dUMP to dTMP via Thymidylate synthase converts the cofactor _____ to DHF

Ribose-5-phosphate is converted to _____ via the enzyme PRPP synthetase

Hypoxanthine may be converted to _____ via the enzyme xanthine oxidase and guanine is converted to xanthine by guanine deaminase