Metabolic Regulation: Substrate Availability — Flashcards

Glucagon acts on the _____ (primarily) and adipose tissue

After three days of starvation, the main source of energy for the brain becomes _____ from adipose stores

Which metabolic enzymes require an obligate activator? 1. _____2. Carbamoyl phosphate synthetase I (N-acetylglutamate)

_____ reactions are chemical reactions that form intermediates of a metabolic pathway.

Glucagon causes _____ fatty acid synthesis and increased lipolysis, which shunts substrates towards gluconeogenesis

_____ deficiency causes a buildup of pyruvate that gets shunted to lactate (via LDH) and alanine (via ALT)

Effect of diabetes on hepatic glycolysis: no answer _____ - No PFK-2 due to lack of insulin - No glucose trapping in liver leads to elevated blood glucose (hyperglycemia)

Increased NADH/NAD+ (e.g. due to ethanol) causes increased conversion of _____ -> malate, thus preventing gluconeogenesis