Lipid Metabolism — Flashcards

Decreased _____ or alteration in its metabolism results in mitochondrial dysfunction seen in Barth syndrome (cardioskeletal myopathy).

Increased NADH/NAD+ (e.g. due to ethanol) causes increased conversion of dihydroxyacetone phosphate -> _____, which combines with fatty acids to make triglycerides, leading to hepatosteatosis (liver pathology)

A major step in the conversion of Arachidonic acids (AA) to leukotrienes is the conversion to _____ by the enzyme 5-lipooxygenase

Hormone sensitive lipase is regulated via positive feedback by _____ and cortisol

Medium chain acyl-CoA deydrogenase (MCAD) deficiency is characterized by _____-ketotic, hypo-glycemia

Free fatty acids (from triglycerides) can be used for energy by the _____ and skeletal muscle

_____ is a PUFA containing 6 double bonds

In preparation for -oxidation, fatty acids in the intermembrane space are converted to _____ via the enzyme fatty acyl-CoA synthetase

17-hydroxyprogesterone may be converted to _____ via the enzyme 17,20-lyase

The chylomicron remnant expresses only apolipoprotein _____ and E on its surface