Lipid Metabolism — Flashcards

Increased NADH/NAD+ (e.g. due to ethanol) causes increased conversion of dihydroxyacetone phosphate -> _____, which combines with fatty acids to make triglycerides, leading to hepatosteatosis (liver pathology)

In the intermembrane space, fatty acyl-CoA is converted to _____ via the enzyme carnitine palmitoyl transferase 1 (CPT1)

Decreased _____ or alteration in its metabolism results in mitochondrial dysfunction seen in Barth syndrome (cardioskeletal myopathy).

Free fatty acids (from triglycerides) can be used for energy by the _____ and skeletal muscle

Acetyl-CoA carboxylase is inhibited by _____ and palmitoyl CoA

What are the three ketone bodies? 1. _____ 2. Beta-hydroxybutyrate 3. Acetone

17-hydroxypregnenolone may be converted to _____ via the enzyme 3-hydroxysteroid dehydrogenase

17-hydroxyprogesterone may be converted to _____ via the enzyme 17,20-lyase

Fatty acyl-CoA is broken down into molecules of _____ via the enzyme acyl-CoA dehydrogenase (β-oxidation)

The enzyme _____, present in the endoplasmic reticulum, catalyzes the conversion of stearic acid (a saturated fatty acid) to oleic acid, which is a MUFA.