Lipid Metabolism — Flashcards

Type _____ familial dyslipidemia is due to either:- absent or defective LDL receptors - defective Apo B-100

Peroxisomal beta-oxidation of VLCFAs lead to the formation of _____ and H2O2

In extrahepatic tissues, acetoacetate is activated to _____ via the enzyme thiophorase (ketone body metabolism)

Sphingomyelin is converted to _____ via the enzyme sphingomyelinase

Type _____ familial dyslipidemia is due to a defective Apo E allele

Apoprotein _____ is an activator of the enzyme LCAT (lecithin cholesterol acyltransferase)

The IDL expresses only apolipoprotein _____ and E on its surface

Dehydroepiandrosterone (DHEA) may be converted to _____ via the enzyme 3-hydroxysteroid dehydrogenase

Cholesterol synthesis:Cyclization of _____ to give rise to the parent steroid, lanosterol

_____ -carbon steroids have estrogenic activity