Lipid Metabolism — Flashcards

_____-carbon steroids, such as DHEA and androstenedione, have androgenic activity and are precursors to estrogen

_____ is released from the phospholipid cell membrane by the enzyme phospholipase A2

Fatty acid synthesis requires _____, which is provided directly from citrate

Type _____ familial dyslipidemia is due to either:- absent or defective LDL receptors - defective Apo B-100

Fatty acid synthesis predominantly occurs in the _____, lactating mammary glands (women), and adipose tissue

Cholesterol synthesis:Condensation of six _____ units form squalene

Peroxisomal beta-oxidation of VLCFAs lead to the formation of _____ and H2O2

In extrahepatic tissues, acetoacetate is activated to _____ via the enzyme thiophorase (ketone body metabolism)

Malonyl-CoA may be converted to _____ via the enzyme fatty acid synthase

Once depleted of their triglycerides, chylomicron _____ return to the liver