Mitochondrial Diseases — Flashcards

NADH electrons from glycolysis enter the mitochondria via the _____ or glycerol-3-phosphate shuttle

Increased NADH/NAD+ (e.g. due to ethanol) causes increased conversion of _____ -> lactate, thus increasing risk for lactic acidosis

Neuropathy Ataxia Retinitis Pigmentosa syndrome is described as a _____ function disorder.

Propionyl-CoA is converted to _____ via the enzyme propionyl-CoA carboxylase

Creatine phosphate occurs in vertebrate skeletal muscle, _____, spermatozoa, and brain.

_____ is combined with oxaloacetate via the enzyme citrate synthase, forming citrate

Isocitrate is converted to _____ via the enzyme isocitrate dehydrogenase

_____ is an inhibitor of complex III of the ETC

Thyroid Peroxidase is involved in the second part of T4 synthesis, generating _____ and T4 bound to thyroglobulin

O2 is converted to _____ by the enzyme NADPH oxidase (oxidative burst)